37 citations · 122 across the 8 of their papers we have counts for
8 papers
Getting higher on rugged landscapes: Inversion mutations open access to fitter adaptive peaks in NK fitness landscapes
Leonardo Trujillo, Paul Banse, Guillaume Beslon
Molecular evolution is often conceptualised as adaptive walks on rugged fitness landscapes, driven by mutations and constrained by incremental fitness selection. It is well known t…
Variable length genetic algorithm with continuous parameters optimization of beam layout in proton therapy
François Smekens, Nicolas Freud, Bruno Sixou +2
Proton therapy is a modality in fast development. Characterized by a maximum dose deposition at the end of the proton trajectory followed by a sharp fall-off, proton beams can deli…
Towards the optimization of ballistics in proton therapy using genetic algorithms: implementation issues
François Smekens, Nicolas Freud, Bruno Sixou +2
The dose delivered to the planning target volume by proton beams is highly conformal, sparing organs at risk and normal tissues. New treatment planning systems adapted to spot scan…
Simulating short- and long-term evolutionary dynamics on rugged landscapes
Leonardo Trujillo, Paul Banse, Guillaume Beslon
We propose a minimal model to simulate long waiting times followed by evolutionary bursts on rugged landscapes. It combines point and inversions-like mutations as sources of geneti…
The Surprising Creativity of Digital Evolution: A Collection of Anecdotes from the Evolutionary Computation and Artificial Life Research Communities
Joel Lehman, Jeff Clune, Dusan Misevic +50
Biological evolution provides a creative fount of complex and subtle adaptations, often surprising the scientists who discover them. However, because evolution is an algorithmic pr…
Anomalous versus slowed-down Brownian diffusion in the ligand-binding equilibrium
Hédi Soula, Bertrand Caré, Guillaume Beslon +1
Measurements of protein motion in living cells and membranes consistently report transient anomalous diffusion (subdiffusion) which converges back to a Brownian motion with reduced…
Complex Systems Science: Dreams of Universality, Reality of Interdisciplinarity
Sebastian Grauwin, Guillaume Beslon, Eric Fleury +4
Using a large database (~ 215 000 records) of relevant articles, we empirically study the "complex systems" field and its claims to find universal principles applying to systems in…
French Roadmap for complex Systems 2008-2009
Paul Bourgine, David Chavalarias, Edith Perrier +78
This second issue of the French Complex Systems Roadmap is the outcome of the Entretiens de Cargese 2008, an interdisciplinary brainstorming session organized over one week in 2008…