activity
20092013
most citedThe rate of decline of CD4 T-cells in people infected with HIV

8 citations · 21 across the 6 of their papers we have counts for

collaborators

6 papers

q-bio.QM2013

Could ART increase the population level incidence of TB?

Brian Gerard Williams

HIV increases the likelihood that a person will develop TB. Starting them on anti-retroviral therapy (ART) reduces their risk of TB but not to the level in HIV negative people. Sin…

q-bio.QM20121 cited

HIV, TB and ART: the CD4 enigma

Brian Williams, Eleanor Gouws

The concentration of CD4 T-lymphocytes (CD4 count), in a person's plasma is widely used to decide when to start HIV-positive people on anti-retroviral therapy (ART) and to predict…

q-bio.PE20123 cited

Pre-exposure prophylaxis (PrEP) versus treatment-as-prevention (TasP) for the control of HIV: Where does the balance lie?

Brian G. Williams, Eleanor Gouws, John Hargrove +2

Anti-retroviral drugs can reduce the infectiousness of people living with HIV by about 96%--treatment as prevention or TasP--and can reduce the risk of being infected by an HIV pos…

q-bio.QM20123 cited

Anti-retroviral therapy for HIV: who should we test and who should we treat?

Brian G. Williams, Renier van Rooyen, Martin Nieuwoudt

In most countries CD4+ cell counts are still used for deciding when to start HIV-positive people on anti-retroviral therapy. However, various CD4+ thresholds, 200, 350 or 500/\muL,…

q-bio.CB20116 cited

Resistance to TB drugs in KwaZulu-Natal: causes and prospects for control

Kristina Wallengren, Fabio Scano, Paul Nunn +9

In 2005 there was an outbreak of XDR (extensively drug resistant) TB in Tugela Ferry, which is served by the Church of Scotland Hospital (COSH), in the uMzinyathi District, KwaZulu…

q-bio.CB20098 cited

The rate of decline of CD4 T-cells in people infected with HIV

Brian G. Williams, Eline L. Korenromp, Eleanor Gouws +1

In people infected with HIV the RNA viral load is a good predictor of the rate of loss of CD4 cells at a population level but there is still great variability in the rate of declin…