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20082015
most citedDescription of non-specific DNA-protein interaction and facilitated diffusion with a dynamical model

42 citations · 171 across the 9 of their papers we have counts for

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physics.bio-ph2015★ 3 cited

A molecule that detects the length of DNA by using chain fluctuations

Kuni H. Iwasa, Ana Maria Florescu

A class of nucleosome remodeling motors translocate nucleosomes, to which they are attached, toward the middle of DNA chain in the presence of ATP during in vitro experiments. Such…

physics.bio-ph2015★ 11 cited

Free energy landscape and characteristic forces for the initiation of DNA unzipping

Ahmet Mentes, Ana Maria Florescu, Elizabeth Brunk +3

DNA unzipping, the separation of its double helix into single strands, is crucial in modulating a host of genetic processes. Although the large-scale separation of double-stranded…

physics.bio-ph2011★ 19 cited

Thermal and mechanical denaturation properties of a DNA model with three sites per nucleotide

Ana-Maria Florescu, Marc Joyeux

In this paper, we show that the coarse grain model for DNA, which has been proposed recently by Knotts, Rathore, Schwartz and de Pablo (J. Chem. Phys. 126, 084901 (2007)), can be a…

physics.bio-ph2010★ 27 cited

Comparison of kinetic and dynamical models of DNA-protein interaction and facilitated diffusion

Ana-Maria Florescu, Marc Joyeux

It has long been asserted that proteins like transcription factors may locate their target in DNA sequences at rates that surpass by several orders of magnitude the three-dimension…

physics.bio-ph2009★ 22 cited

Dynamical model of DNA-protein interaction: effect of protein charge distribution and mechanical properties

Ana-Maria Florescu, Marc Joyeux

The mechanical model based on beads and springs, which we recently proposed to study non-specific DNA-protein interactions [J. Chem. Phys. 130, 015103 (2009)], was improved by desc…

physics.bio-ph2008★ 42 cited

Description of non-specific DNA-protein interaction and facilitated diffusion with a dynamical model

Ana-Maria Florescu, Marc Joyeux

We propose a dynamical model for non-specific DNA-protein interaction, which is based on the 'bead-spring' model previously developed by other groups, and investigate its propertie…