115 citations · 158 across the 5 of their papers we have counts for
5 papers
Overcoming the limitations of the MARTINI force field in Molecular Dynamics simulations of polysaccharides
Philipp S. Schmalhorst, Felix Deluweit, Roger Scherrers +2
Polysaccharides (carbohydrates) are key regulators of a large number of cell biological processes. However, precise biochemical or genetic manipulation of these often complex struc…
Formation of Cystine Slipknots in Dimeric Proteins
Mateusz Sikora, Marek Cieplak
We consider mechanical stability of dimeric and monomeric proteins with the cystine knot motif. A structure based dynamical model is used to demonstrate that all dimeric and some m…
Cystine plug and other novel mechanisms of large mechanical stability in dimeric proteins
Mateusz Sikora, Marek Cieplak
We identify three dimeric proteins whose mechanostability is anisotropic and should exceed 1 nN along some directions. They come with distinct mechanical clamps: shear-based, invol…
Molecular jamming - the cystine slipknot mechanical clamp in all-atom simulations
Lukasz Peplowski, Mateusz Sikora, Wieslaw Nowak +1
A recent survey of 17 134 proteins has identified a new class of proteins which are expected to yield stretching induced force-peaks in the range of 1 nN. Such high force peaks sho…
Mechanical Strength of 17 134 Model Proteins and Cysteine Slipknots
Mateusz Sikora, Joanna I. Sułkowska, Marek Cieplak
A new theoretical survey of proteins' resistance to constant speed stretching is performed for a set of 17 134 proteins as described by a structure-based model. The proteins select…