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stat.AP2026

Longitudinal wearable monitoring and polygenic risk for incident major depressive disorder in the All of Us Research Program

Yuezhou Zhang, Amos A. Folarin, Rongrong Zhong +4

Major depressive disorder (MDD) risk reflects both stable inherited liability and dynamic behavioral patterns, yet these dimensions are rarely examined together using long-term obj…

stat.AP2026

Preoperative Decline and Postoperative Recovery of Wearable-Derived Physical Activity Over a Four-Year Perioperative Period in Total Knee and Hip Arthroplasty: Evidence from the All of Us Research Program

Yuezhou Zhang, Amos Folarin, Callum Stewart +4

Total knee arthroplasty (TKA) and total hip arthroplasty (THA) improve symptoms in end-stage osteoarthritis, yet long-term objective characterization of perioperative physical acti…

stat.AP2026

Physical Activity Trajectories Preceding Incident Major Depressive Disorder Diagnosis Using Consumer Wearable Devices in the All of Us Research Program: Case-Control Study

Yuezhou Zhang, Amos Folarin, Hugh Logan Ellis +7

Low physical activity is a known risk factor for major depressive disorder (MDD), but changes in activity before a first clinical diagnosis remain unclear, especially using long-te…

stat.AP2024

Deciphering seasonal depression variations and interplays between weather changes, physical activity, and depression severity in real-world settings: Learnings from RADAR-MDD longitudinal mobile health study

Yuezhou Zhang, Amos A. Folarin, Yatharth Ranjan +20

Prior research has shown that changes in seasons and weather can have a significant impact on depression severity. However, findings are inconsistent across populations, and the in…