4 papers
UniD: A Knowledge Graph-Enhanced RAG Framework for Drug-Disease Discovery and Reasoning
Qing Wang, Tianshi Liu, Minghao Zhou +5
Systematic characterization of drug-disease relationships is essential for drug discovery and repurposing, yet is hindered by the heterogeneity and rapid growth of biomedical liter…
Hy-Facial: Hybrid Feature Extraction by Dimensionality Reduction Methods for Enhanced Facial Expression Classification
Xinjin Li, Yu Ma, Kaisen Ye +3
Facial expression classification remains a challenging task due to the high dimensionality and inherent complexity of facial image data. This paper presents Hy-Facial, a hybrid fea…
scDrugMap: Benchmarking Large Foundation Models for Drug Response Prediction
Qing Wang, Yining Pan, Minghao Zhou +4
Drug resistance presents a major challenge in cancer therapy. Single cell profiling offers insights into cellular heterogeneity, yet the application of large-scale foundation model…
PhenoProfiler: Advancing Phenotypic Learning for Image-based Drug Discovery
Bo Li, Bob Zhang, Chengyang Zhang +7
In the field of image-based drug discovery, capturing the phenotypic response of cells to various drug treatments and perturbations is a crucial step. However, existing methods req…