5 papers
DrugClaw and DrugAudit: A Primary-Source-Grounded Agent and Authority-Aware Benchmark for Drug-Information Question Answering
Qing Wang, Bo Li, Jialu Liang +3
Drug-information question answering is a high-stakes setting where hallucinated facts can mislead clinical decision-making and the provenance of each cited fact matters as much as…
UniD: A Knowledge Graph-Enhanced RAG Framework for Drug-Disease Discovery and Reasoning
Qing Wang, Tianshi Liu, Minghao Zhou +5
Systematic characterization of drug-disease relationships is essential for drug discovery and repurposing, yet is hindered by the heterogeneity and rapid growth of biomedical liter…
scDrugMap: Benchmarking Large Foundation Models for Drug Response Prediction
Qing Wang, Yining Pan, Minghao Zhou +4
Drug resistance presents a major challenge in cancer therapy. Single cell profiling offers insights into cellular heterogeneity, yet the application of large-scale foundation model…
PhenoProfiler: Advancing Phenotypic Learning for Image-based Drug Discovery
Bo Li, Bob Zhang, Chengyang Zhang +7
In the field of image-based drug discovery, capturing the phenotypic response of cells to various drug treatments and perturbations is a crucial step. However, existing methods req…
HECLIP: Histology-Enhanced Contrastive Learning for Imputation of Transcriptomics Profiles
Qing Wang, Wen-jie Chen, Bo Li +3
Histopathology, particularly hematoxylin and eosin (H\&E) staining, plays a critical role in diagnosing and characterizing pathological conditions by highlighting tissue morphology…