3 papers
q-bio.GN2026
PlantBGC: Transformer for Plant BGC Discovery via Label-Free Domain Adaptation and Weak Supervision
Yuhan Zhao, Nidhi Grover, Zhishan Guo +1
Plant biosynthetic gene clusters (BGCs) encode specialized-metabolite pathways, yet curated plant BGC labels remain scarce, hindering supervised discovery at genome scale. Existing…
cs.LG2026
DeepDTF: Dual-Branch Transformer Fusion for Multi-Omics Anticancer Drug Response Prediction
Yuhan Zhao, Jacob Tennant, James Yang +3
Cancer drug response varies widely across tumors due to multi-layer molecular heterogeneity, motivating computational decision support for precision oncology. Despite recent progre…
q-bio.BM2024
Pre-trained Molecular Language Models with Random Functional Group Masking
Tianhao Peng, Yuchen Li, Xuhong Li +7
Recent advancements in computational chemistry have leveraged the power of trans-former-based language models, such as MoLFormer, pre-trained using a vast amount of simplified mole…