6 papers
From Holo Pockets to Electron Density: GPT-style Drug Design with Density
Jiahao Chen, Letian Gao, Yanhao Zhu +4
Recent advances in generative modeling have enabled significant progress in structure-based drug design (SBDD). Existing methods typically condition molecule generation on empty bi…
Pareto-Guided Optimal Transport for Multi-Reward Alignment
Ying Ba, Tianyu Zhang, Mohan Zhou +5
Text-to-image generation models have achieved remarkable progress in preference optimization, yet achieving robust alignment across diverse reward models remains a significant chal…
SciLT: Long-tailed Image Classification under Scientific Image Domains
Jiahao Chen, Bing Su
Long-tailed recognition has benefited from foundation models and fine-tuning paradigms, yet existing studies and benchmarks are mainly confined to natural image domains, where pre-…
LoFT: Parameter-Efficient Fine-Tuning for Long-tailed Semi-Supervised Learning in Open-World Scenarios
Zhiyuan Huang, Jiahao Chen, Bing Su
Long-tailed semi-supervised learning (LTSSL) presents a formidable challenge where models must overcome the scarcity of tail samples while mitigating the noise from unreliable pseu…
Interpretable Enzyme Function Prediction via Residue-Level Detection
Zhao Yang, Bing Su, Jiahao Chen +1
Predicting multiple functions labeled with Enzyme Commission (EC) numbers from the enzyme sequence is of great significance but remains a challenge due to its sparse multi-label cl…
LumosFlow: Motion-Guided Long Video Generation
Jiahao Chen, Hangjie Yuan, Yichen Qian +6
Long video generation has gained increasing attention due to its widespread applications in fields such as entertainment and simulation. Despite advances, synthesizing temporally c…