13 citations · 13 across the 3 of their papers we have counts for
4 papers
VARIANT: Web Server for Decoding and Analyzing Viral Mutations at Genome and Protein Levels
Rui Wang, Xuhang Dai, Xin Cao +3
A comprehensive analysis of viral mutations is essential for understanding viral evolution, disease epidemiology, diagnosis, drug resistance, etc. However, challenges remain in cap…
Rapid response to fast viral evolution using AlphaFold 3-assisted topological deep learning
JunJie Wee, Guo-Wei Wei
The fast evolution of SARS-CoV-2 and other infectious viruses poses a grand challenge to the rapid response in terms of viral tracking, diagnostics, and design and manufacture of m…
Benchmarking AlphaFold3's protein-protein complex accuracy and machine learning prediction reliability for binding free energy changes upon mutation
JunJie Wee, Guo-Wei Wei
AlphaFold 3 (AF3), the latest version of protein structure prediction software, goes beyond its predecessors by predicting protein-protein complexes. It could revolutionize drug di…
Multiscale Topology in Interactomic Network: From Transcriptome to Antiaddiction Drug Repurposing
Hongyan Du, Guo-Wei Wei, Tingjun Hou
The escalating drug addiction crisis in the United States underscores the urgent need for innovative therapeutic strategies. This study embarked on an innovative and rigorous strat…