5 papers
HonestAffinity: Leak-Aware Evaluation of Protein and Pocket Priors for Binding Affinity Prediction
Junhao Wei, Baili Lu, Zhenhong Peng +10
Sequence-based deep learning offers a scalable alternative to structure-based scoring for protein-ligand binding affinity prediction. However, progress is hard to interpret when ar…
Disentangled Instrumental Variables for Causal Inference with Networked Observational Data
Zhirong Huang, Debo Cheng, Guixian Zhang +3
Instrumental variables (IVs) are crucial for addressing unobservable confounders, yet their stringent exogeneity assumptions pose significant challenges in networked data. Existing…
Interaction-Data-guided Conditional Instrumental Variables for Debiasing Recommender Systems
Zhirong Huang, Debo Cheng, Jiuyong Li +3
It is often challenging to identify a valid instrumental variable (IV), although the IV methods have been regarded as effective tools of addressing the confounding bias introduced…
Multi-Cause Deconfounding for Recommender Systems with Latent Confounders
Zhirong Huang, Shichao Zhang, Debo Cheng +3
In recommender systems, various latent confounding factors (e.g., user social environment and item public attractiveness) can affect user behavior, item exposure, and feedback in d…
Debiased Contrastive Representation Learning for Mitigating Dual Biases in Recommender Systems
Zhirong Huang, Shichao Zhang, Debo Cheng +3
In recommender systems, popularity and conformity biases undermine recommender effectiveness by disproportionately favouring popular items, leading to their over-representation in…