17 citations · 32 across the 4 of their papers we have counts for
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q-bio.BM2024★ 10 cited
PepTune: De Novo Generation of Therapeutic Peptides with Multi-Objective-Guided Discrete Diffusion
Sophia Tang, Yinuo Zhang, Pranam Chatterjee
We present PepTune, a multi-objective discrete diffusion model for simultaneous generation and optimization of therapeutic peptide SMILES. Built on the Masked Discrete Language Mod…
q-bio.BM2024★ 5 cited
PepDoRA: A Unified Peptide Language Model via Weight-Decomposed Low-Rank Adaptation
Leyao Wang, Rishab Pulugurta, Pranay Vure +3
Peptide therapeutics, including macrocycles, peptide inhibitors, and bioactive linear peptides, play a crucial role in therapeutic development due to their unique physicochemical p…