activity
20232026
most citedLimits on Inferring T-cell Specificity from Partial Information

18 citations · 22 across the 5 of their papers we have counts for

collaborators

5 papers

q-bio.PE2026

Fluctuating environments are sufficient to drive substantial variability in species abundance across locations

James F. D. Henderson, Andreas Tiffeau-Mayer

Species growing in environments that change in time and space will vary in their abundance across locations, even in the absence of persistent location preferences. Here we quantif…

q-bio.BM2024★ 1 cited

Data-driven Discovery of Biophysical T Cell Receptor Co-specificity Rules

Andrew G. T. Pyo, Yuta Nagano, Martina Milighetti +5

The biophysical interactions between the T cell receptor (TCR) and its ligands determine the specificity of the cellular immune response. However, the immense diversity of receptor…

q-bio.BM2024★ 2 cited

Contrastive learning of T cell receptor representations

Yuta Nagano, Andrew Pyo, Martina Milighetti +4

Computational prediction of the interaction of T cell receptors (TCRs) and their ligands is a grand challenge in immunology. Despite advances in high-throughput assays, specificity…

q-bio.BM2024★ 18 cited

Limits on Inferring T-cell Specificity from Partial Information

James Henderson, Yuta Nagano, Martina Milighetti +1

A key challenge in molecular biology is to decipher the mapping of protein sequence to function. To perform this mapping requires the identification of sequence features most infor…

q-bio.PE2023★ 1 cited

Unbiased estimation of sampling variance for Simpson's diversity index

Andreas Tiffeau-Mayer

Quantification of measurement uncertainty is crucial for robust scientific inference, yet accurate estimates of this uncertainty remain elusive for ecological measures of diversity…