Preservation Constraints on aDNA Information Generation and the HSF Posterior Sourcing Framework: A First-Principles Critique of Conventional Methods

Wan-Qian Zhao, Shu-Jie Zhang, Zhan-Yong Guo +1

Fossil DNA preservation varies with depositional environments and diagenesis, producing fragments of heterogeneous origins and degradation states. We use first-principles biomolecu…