5 citations · 8 across the 5 of their papers we have counts for
4 papers · 1 filter
Sampling-based Continuous Optimization for Messenger RNA Design
Feipeng Yue, Ning Dai, Wei Yu Tang +3
Designing messenger RNA (mRNA) sequences for a fixed target protein requires searching an exponentially large synonymous space while optimizing properties that affect stability and…
Sampling-based Continuous Optimization with Coupled Variables for RNA Design
Wei Yu Tang, Ning Dai, Tianshuo Zhou +2
The task of RNA design given a target structure aims to find a sequence that can fold into that structure. It is a computationally hard problem where some version(s) have been prov…
Messenger RNA Design via Expected Partition Function and Continuous Optimization
Ning Dai, Wei Yu Tang, Tianshuo Zhou +2
The tasks of designing RNAs are discrete optimization problems, and several versions of these problems are NP-hard. As an alternative to commonly used local search methods, we form…
Undesignable RNA Structure Identification via Rival Structure Generation and Structure Decomposition
Tianshuo Zhou, Wei Yu Tang, David H. Mathews +1
RNA design is the search for a sequence or set of sequences that will fold into predefined structures, also known as the inverse problem of RNA folding. While numerous RNA design m…