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stat.ME2024
The Estimand Framework and Causal Inference: Complementary not Competing Paradigms
Thomas Drury, Jonathan W. Bartlett, David Wright +1
The creation of the ICH E9 (R1) estimands framework has led to more precise specification of the treatment effects of interest in the design and statistical analysis of clinical tr…
stat.ME2024★ 2 cited
Estimands and Their Implications for Evidence Synthesis for Oncology: A Simulation Study of Treatment Switching in Meta-Analysis
Rebecca K. Metcalfe, Antonio Remiro-Azócar, Quang Vuong +4
The ICH E9(R1) addendum provides guidelines on accounting for intercurrent events in clinical trials using the estimands framework. However, there has been limited attention to the…