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stat.ME2023
Semi-parametric Benchmark Dose Analysis with Monotone Additive Models
Alex Stringer, Tugba Akkaya Hocagil, Richard Cook +3
Benchmark dose analysis aims to estimate the level of exposure to a toxin that results in a clinically-significant adverse outcome and quantifies uncertainty using the lower limit…
stat.ME2023
Exact Gradient Evaluation for Adaptive Quadrature Approximate Marginal Likelihood in Mixed Models for Grouped Data
Alex Stringer
A method is introduced for approximate marginal likelihood inference via adaptive Gaussian quadrature in mixed models with a single grouping factor. The core technical contribution…