3 papers
q-bio.QM2025
A Simple Voltage-Modulated Markov Chain Model for the Piezo1 Ion Channel to Investigate Electromechanical Pacing
Dennis Ogiermann, Abdulaziz Mohamed, Luigi E. Perotti +1
Piezo1 ion channels are voltage-modulated, stretch-activated ion channels involved in a variety of important physiological and pathophysiological processes, as for example cardiova…
math.NA2023
An Explicit Local Space-Time Adaptive Framework for Monodomain Models
Dennis Ogiermann, Daniel Balzani, Luigi E. Perotti
We present a new explicit local space-time adaptive framework to decrease the time required for monodomain simulations for cardiac electrophysiology. Based on the localized structu…
math.NA2023
Computational Modeling of Coupled Interactions of Fluid Membranes with Embedded Filaments
Basant Lal Sharma, Luigi E. Perotti, Sanjay Dharmavaram
In this work, we present a computational formulation based on continuum mechanics to study the interaction of fluid membranes embedded with semiflexible filaments. This is motivate…