11 citations · 16 across the 5 of their papers we have counts for
5 papers
Impact of Oxygen on DNA Damage Distribution in 3D Genome and its Correlation to Oxygen Enhancement Ratio after High-LET Irradiation
Ankang Hu, Wanyi Zhou, Xiyu Luo +2
The variation of the oxygen enhancement ratio (OER) across linear energy transfer (LET) currently lacks a comprehensive mechanistic interpretation and a mechanistic model. Our earl…
Correlation Between DNA Double-Strand Break Distribution in 3D Genome and Radiation-Induced Cell Death
Ankang Hu, Wanyi Zhou, Xiyu Luo +2
The target theory is the most classical hypothesis explaining radiation-induced cell death, the physical or biological nature of the "target" remains ambiguous. This study hypothes…
Influencing Factors of the FLASH Effect: Unveiling the Importance of Free Radicals
Yan Zhang, Chenyang Huang, Ankang Hu +10
Purpose: Our aim was to elucidate the critical factors responsible for inducing the FLASH effect, focusing on the role of free radicals through simulation and experimental approach…
Mathematical Analysis of FLASH Effect Models Based on Theoretical Hypotheses
Ankang Hu, Wanyi Zhou, Rui Qiu +1
Clinical applications of FLASH radiotherapy require formulas to describe how the FLASH radiation features and other related factors determine the FLASH effect. Mathematical analysi…
Oxygen depletion hypothesis remains controversial: a mathematical model of oxygen depletion during FLASH radiation
Ankang Hu, Rui Qiu, Zhen Wu +3
Background: Experiments have reported low normal tissue toxicities during FLASH radiation, but the mechanism has not been elaborated. Several hypotheses have been proposed to expla…