2 papers
q-bio.MN2025
Mapping disease-regulatory flux through eQTL-based causal gene networks: a complex-trait framework applied to coronary artery disease
Gutama Ibrahim Mohammad, Johan LM Björkegren, Tom Michoel
A substantial proportion of inherited susceptibility to common diseases is mediated through tissue-specific regulatory variation. The omnigenic model hypothesizes that much of this…
q-bio.MN2024
Predicting the genetic component of gene expression using gene regulatory networks
Gutama Ibrahim Mohammad, Tom Michoel
Gene expression prediction plays a vital role in transcriptome-wide association studies (TWAS), which seek to establish associations between tissue gene expression and complex trai…