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physics.bio-ph2026
DNA end tethering through break-induced DNA--protein condensation
Rakesh Das, Tarun Mascarenhas, Nagaraja Chappidi +2
Cells deploy robust mechanisms to repair DNA damage, safeguarding genomic stability and cellular health, but the physical principles underlying these processes remain incompletely…
physics.bio-ph2026
In vitro binding energies capture Klf4 occupancy across the human genome
Anne Schwager, Jonas Neipel, Yahor Savich +4
Transcription factors (TFs) regulate gene expression by binding to specific genomic loci determined by DNA sequence. Their sequence specificity is commonly summarized by a consensu…
physics.bio-ph2025
A Model for Self-Organized Growth, Branching, and Allometric Scaling of the Planarian Gut
Christian Hanauer, Amrutha Palavalli, Baiqun An +3
The growth and scaling of organs is a fundamental aspect of animal development. However, how organs grow to the right size and shape required by physiological demands, remains larg…