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math.OC2025
Mixed-Integer Optimization for Loopless Flux Distributions in Metabolic Networks
Hannah Troppens, Mathieu Besançon, St. Elmo Wilken +1
Constraint-based metabolic models can be used to investigate the intracellular physiology of microorganisms. These models couple genes to reactions, and typically seek to predict m…
math.OC2025
Improved algorithms and novel applications of the FrankWolfe.jl library
Mathieu Besançon, Sébastien Designolle, Jannis Halbey +6
Frank-Wolfe (FW) algorithms have emerged as an essential class of methods for constrained optimization, especially on large-scale problems. In this paper, we summarize the algorith…