4 papers
IRIS: time-structured manifold projections
Brian Ondov, Chia-Hsuan Chang, Weipeng Zhou +6
High-dimensional biomedical data, such as cell-by-gene matrices, are increasingly generated temporally. However, Manifold Learning algorithms, like t-SNE and UMAP, cannot incorpora…
Foundation Models to Unlock Real-World Evidence from Nationwide Medical Claims
Fan Ma, Yuntian Liu, Xiang Lan +22
Evidence derived from large-scale real-world data (RWD) is increasingly informing regulatory evaluation and healthcare decision-making. Administrative claims provide population-sca…
Toward Federated Large Language Models in Medicine: A Parameter-Efficient Framework for Privacy-Preserving, Multi-Institutional Adaptation
Anran Li, Yuanyuan Chen, Wenjun Long +16
Large language models (LLMs) are increasingly adapted for medical applications, but most are trained using data from a single institution because privacy and governance constraints…
Fino1: On the Transferability of Reasoning-Enhanced LLMs and Reinforcement Learning to Finance
Lingfei Qian, Weipeng Zhou, Yan Wang +6
As the fundamental capability behind decision-making in finance, financial reasoning poses distinct challenges for LLMs. Although reinforcement learning (RL) have boosted generic r…