3 papers
q-bio.QM2026
A vision foundation model for single-cell biology via spatial gene cartography
Ridvan Yesiloglu, Sakib Mostafa, James Zou +5
Most single-cell foundation models are adapted from language models, representing each cell as a sequence of gene tokens. This discards the relationships among genes and often the…
cs.LG2026
Knowledge Graph Modulated Deep Learning for Limited-Sample Clinical Data Analysis
Yuwei Xue, Sakib Mostafa, James Zou +5
Biological systems are governed by structured molecular interactions, where pathways, regulatory circuits, and functional gene relationships shape cellular behavior and disease pro…
cs.LG2025
LLM-Lasso: A Robust Framework for Domain-Informed Feature Selection and Regularization
Erica Zhang, Ryunosuke Goto, Naomi Sagan +7
We introduce LLM-Lasso, a novel framework that leverages large language models (LLMs) to guide feature selection in Lasso regression. Unlike traditional methods that rely…