9 citations · 12 across the 5 of their papers we have counts for
5 papers
Epistatic strength, modularity, and locus heterogeneity shape the number of local optima in fitness landscapes
Mahan Ghafari, Alejandro Castro Cabrera, Alejandro Lage-Castellanos +3
Fitness landscapes provide a quantitative framework for understanding how natural selection shapes evolutionary trajectories. A central feature of these landscapes is their number…
Simple sign epistasis and evolutionary detours in fitness landscapes
Paolo Ribeca, Alejandro Castro, Alejandro Lage-Castellanos +8
In epistatic fitness landscapes, the fitness effect of a mutation depends on the genetic background and may even switch between deleterious and beneficial depending on the presence…
Evolution as fitness landscape navigation: concepts, measures, and emerging questions
Malvika Srivastava, Claudia Bank, Joachim Krug +1
Fitness landscapes are mappings between genotypes, phenotypes, and fitness that shape evolution. In recent years, empirical work and theoretical models have greatly advanced our un…
Complexity and accessibility of random landscapes
Sakshi Pahujani, Joachim Krug
These notes introduce probabilistic landscape models defined on high-dimensional discrete sequence spaces. The models are motivated primarily by fitness landscapes in evolutionary…
Evolutionary accessibility of random and structured fitness landscapes
Joachim Krug, Daniel Oros
Biological evolution can be conceptualized as a search process in the space of gene sequences guided by the fitness landscape, a mapping that assigns a measure of reproductive valu…