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q-bio.QM2026
Quantifying antiproliferative effects of quinolinic acid on melanoma, macrophage and keratinocyte cells using a parametric cell-viability model
Roumen Anguelov, Charlise Basson, Yvette N. Hlophe +4
This paper presents a robust mathematical framework for quantifying antiproliferative effects from noisy in vitro cell viability experiments. The methodology is demonstrated using…
q-bio.QM2022
Quantifying assays: A Modeling tale of variability in cancer therapeutics assessed on cancer cells
Roumen Anguelov, G Manjunath, Avulundiah E Phiri +4
Inhibiting a signalling pathway concerns controlling the cellular processes of a cancer cell's viability, cell division, and death. Assay protocols created to see if the molecular…