2 papers
q-bio.GN2025
Eukaryotes evade information storage-replication rate trade-off with endosymbiont assistance leading to larger genomes
Parthasarathi Sahu, Sashikanta Barik, Koushik Ghosh +1
Genome length varies widely among organisms, from compact genomes of prokaryotes to vast and complex genomes of eukaryotes. In this study, we theoretically identify the evolutionar…
q-bio.GN2024
High nucleotide skew palindromic DNA sequences function as replication origins due to their unzipping propensity
Parthasarathi Sahu, Sashikanta Barik, Koushik Ghosh +1
Locations of DNA replication initiation in prokaryotes, called "origins of replication", are well-characterized. However, a mechanistic understanding of the sequence-dependence of…