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q-bio.BM2026
Recovering protein conformations from single-particle cryo-EM data via indirect shape matching gradient flows
Erik Jansson, Jonathan Krook, Ozan Öktem +1
Single-particle cryo-electron microscopy images a macromolecule as many noisy tomographic projections of its electrostatic potential. We reconstruct the protein backbone directly f…
q-bio.BM2024
Geometric shape matching for recovering protein conformations from single-particle Cryo-EM data
Erik Jansson, Jonathan Krook, Klas Modin +1
We address recovery of the three-dimensional backbone structure of single polypeptide proteins from single-particle cryo-electron microscopy (Cryo-SPA) data. Cryo-SPA produces nois…