12 papers
Evaluating Large Language Models in Dynamic Clinical Decision-Making with Standardized Patient Cases
Cheng Liang, Pengcheng Qiu, Ya Zhang +3
Large language models (LLMs) are increasingly proposed as clinical agents, yet static, single-turn benchmarks cannot capture how a model dynamically delivers care across an encount…
An Agentic System for Rare Disease Diagnosis with Traceable Reasoning
Weike Zhao, Chaoyi Wu, Yanjie Fan +10
Rare diseases affect over 300 million individuals worldwide, yet timely and accurate diagnosis remains an urgent challenge. Patients often endure a prolonged diagnostic odyssey exc…
Evolving Interactive Diagnostic Agents in a Virtual Clinical Environment
Pengcheng Qiu, Chaoyi Wu, Junwei Liu +11
We present a framework for training large language models (LLMs) as diagnostic agents with reinforcement learning, enabling them to manage multi-turn interactive diagnostic process…
PhenoLIP: Integrating Phenotype Ontology Knowledge into Medical Vision-Language Pretraining
Cheng Liang, Chaoyi Wu, Weike Zhao +3
Recent progress in large-scale CLIP-like vision-language models(VLMs) has greatly advanced medical image analysis. However, most existing medical VLMs still rely on coarse image-te…
End-to-End Agentic RAG System Training for Traceable Diagnostic Reasoning
Qiaoyu Zheng, Yuze Sun, Chaoyi Wu +8
The integration of Large Language Models (LLMs) into healthcare is constrained by knowledge limitations, hallucinations, and a disconnect from Evidence-Based Medicine (EBM). While…
EHR-R1: A Reasoning-Enhanced Foundational Language Model for Electronic Health Record Analysis
Yusheng Liao, Chaoyi Wu, Junwei Liu +12
Electronic Health Records (EHRs) contain rich yet complex information, and their automated analysis is critical for clinical decision-making. Despite recent advances of large langu…