3 papers
stat.AP2025
Bayesian analysis of restricted mean survival time adjusted for covariates using pseudo-observations
Léa Orsini, Emmanuel Lesaffre, Guosheng Yin +3
The difference in restricted mean survival time (RMST) is a clinically meaningful measure to quantify treatment effect in randomized controlled trials, especially when the proporti…
stat.AP2024
Bayesian generalized method of moments applied to pseudo-observations in survival analysis
Léa Orsini, Caroline Brard, Emmanuel Lesaffre +3
Bayesian inference for survival regression modeling offers numerous advantages, especially for decision-making and external data borrowing, but demands the specification of the bas…
stat.AP2018
A multistate model for early decision making in oncology
Ulrich Beyer, David Dejardin, Matthias Meller +2
The development of oncology drugs progresses through multiple phases, where after each phase a decision is made about whether to move a molecule forward. Early phase efficacy decis…