3 papers
q-bio.GN2026
SynLeaF: A Dual-Stage Multimodal Fusion Framework for Synthetic Lethality Prediction Across Pan- and Single-Cancer Contexts
Zheming Xing, Siyuan Zhou, Ruinan Wang +9
Accurate prediction of synthetic lethality (SL) is important for guiding the development of cancer drugs and therapies. SL prediction faces significant challenges in the effective…
cs.LG2025
MSNGO: multi-species protein function annotation based on 3D protein structure and network propagation
Beibei Wang, Boyue Cui, Shiqu Chen +3
Motivation: In recent years, protein function prediction has broken through the bottleneck of sequence features, significantly improving prediction accuracy using high-precision pr…
cs.LG2024
MKDTI: Predicting drug-target interactions via multiple kernel fusion on graph attention network
Yuhuan Zhou, Yulin Wu, Weiwei Yuan +2
Drug-target relationships may now be predicted computationally using bioinformatics data, which is a valuable tool for understanding pharmacological effects, enhancing drug develop…