2 papers
physics.bio-ph2026
Urea-Mediated Solvent Reorganization of Bovine Serum Albumin in an Acid-Induced Expanded Conformation at pH 3.7
Y. Ricardo Espinosa, C. Manuel Carlevaro, C. Gaston Ferrara
Understanding the molecular mechanisms by which denaturants modulate protein structure remains a central challenge in protein biophysics. In this study, molecular dynamics (MD) sim…
physics.bio-ph2025
Molecular Mechanisms Underlying the Effects of Urea and the Structural Dynamics of Bovine Serum Albumin
Y. Ricardo Espinosa, C. Manuel Carlevaro, C. Gastón Ferrara
The disruption of protein structures by denaturants like urea is well studied, though its molecular mechanisms remain unclear. Using Molecular Dynamics (MD) simulations, we investi…