activity
20232025
most citedLabel-free intratissue activity imaging of alveolar organoids with dynamic optical coherence tomography

42 citations · 79 across the 7 of their papers we have counts for

collaborators

7 papers

physics.med-ph2025★ 8 cited

Dynamic-OCT simulation framework based on mathematical models of intratissue dynamics, image formation, and measurement noise

Yuanke Feng, Shumpei Fujimura, Yiheng Lim +6

Dynamic optical coherence tomography (DOCT) enables label-free functional imaging by capturing temporal OCT signal variations caused by intracellular and intratissue motions. Howev…

physics.optics2025★ 1 cited

In vivo dynamic optical coherence tomography of human skin with hardware- and software-based motion correction

Yu Guo, Rion Morishita, Ibrahim Abd El-Sadek +10

In vivo application of dynamic optical coherence tomography (DOCT) is hindered by bulk motion of the sample. We demonstrate DOCT imaging of \invivo human skin by adopting a sample-…

physics.bio-ph2024★ 7 cited

Optical-coherence-tomography-based deep-learning scatterer-density estimator using physically accurate noise model

Thitiya Seesan, Pradipta Mukherjee, Ibrahim Abd El-Sadek +4

We demonstrate a deep-learning-based scatterer density estimator (SDE) that processes local speckle patterns of optical coherence tomography (OCT) images and estimates the scattere…

physics.optics2024★ 3 cited

Multiple scattering suppression for in vivo optical coherence tomography measurement using B-scan-wise multi-focus averaging method

Yiqiang Zhu, Lida Zhu, Yiheng Lim +3

We demonstrate a method that reduces the noise caused by multi-scattering (MS) photons in an \invivo optical coherence tomography image. This method combines a specially designed i…

physics.optics2023★ 8 cited

Polarization-artifact reduction and accuracy improvement of Jones-matrix polarization-sensitive optical coherence tomography by multi-focus averaging

Lida Zhu, Shuichi Makita, Junya Tamaoki +4

Polarization-sensitive optical coherence tomography (PS-OCT) is a promising biomedical imaging tool for differentiation of various tissue properties. However, the presence of multi…

physics.optics2023★ 10 cited

Multi-focus averaging for multiple scattering suppression in optical coherence tomography

Lida Zhu, Shuichi Makita, Junya Tamaoki +4

Multiple scattering is one of the main factors that limits the penetration depth of optical coherence tomography (OCT) in scattering samples. We propose a method termed multi-focus…

physics.bio-ph2023★ 42 cited

Label-free intratissue activity imaging of alveolar organoids with dynamic optical coherence tomography

Rion Morishita, Pradipta Mukherjee, Ibrahim Abd El-Sadek +8

An organoid is a three-dimensional (3D) in vitro cell culture emulating human organs. We applied 3D dynamic optical coherence tomography (DOCT) to visualize the intratissue and int…