5 papers
ProtoPathway: Biologically Structured Prototype-Pathway Fusion for Multimodal Cancer Survival Prediction
Amaya Gallagher-Syed, Costantino Pitzalis, Myles J. Lewis +2
We introduce ProtoPathway, an interpretable-by-design multimodal framework for cancer survival prediction that unifies whole slide imaging and transcriptomics through encoders prod…
BioX-CPath: Biologically-driven Explainable Diagnostics for Multistain IHC Computational Pathology
Amaya Gallagher-Syed, Henry Senior, Omnia Alwazzan +7
The development of biologically interpretable and explainable models remains a key challenge in computational pathology, particularly for multistain immunohistochemistry (IHC) anal…
Going Beyond H&E and Oncology: How Do Histopathology Foundation Models Perform for Multi-stain IHC and Immunology?
Amaya Gallagher-Syed, Elena Pontarini, Myles J. Lewis +2
This study evaluates the generalisation capabilities of state-of-the-art histopathology foundation models on out-of-distribution multi-stain autoimmune Immunohistochemistry dataset…
MUSTANG: Multi-Stain Self-Attention Graph Multiple Instance Learning Pipeline for Histopathology Whole Slide Images
Amaya Gallagher-Syed, Luca Rossi, Felice Rivellese +4
Whole Slide Images (WSIs) present a challenging computer vision task due to their gigapixel size and presence of numerous artefacts. Yet they are a valuable resource for patient di…
Automated segmentation of rheumatoid arthritis immunohistochemistry stained synovial tissue
Amaya Gallagher-Syed, Abbas Khan, Felice Rivellese +4
Rheumatoid Arthritis (RA) is a chronic, autoimmune disease which primarily affects the joint's synovial tissue. It is a highly heterogeneous disease, with wide cellular and molecul…