6 papers
ProtoPathway: Biologically Structured Prototype-Pathway Fusion for Multimodal Cancer Survival Prediction
Amaya Gallagher-Syed, Costantino Pitzalis, Myles J. Lewis +2
We introduce ProtoPathway, an interpretable-by-design multimodal framework for cancer survival prediction that unifies whole slide imaging and transcriptomics through encoders prod…
BioX-CPath: Biologically-driven Explainable Diagnostics for Multistain IHC Computational Pathology
Amaya Gallagher-Syed, Henry Senior, Omnia Alwazzan +7
The development of biologically interpretable and explainable models remains a key challenge in computational pathology, particularly for multistain immunohistochemistry (IHC) anal…
Multimodal Outer Arithmetic Block Dual Fusion of Whole Slide Images and Omics Data for Precision Oncology
Omnia Alwazzan, Amaya Gallagher-Syed, Thomas O. Millner +4
The integration of DNA methylation data with a Whole Slide Image (WSI) offers significant potential for enhancing the diagnostic precision of central nervous system (CNS) tumor cla…
Going Beyond H&E and Oncology: How Do Histopathology Foundation Models Perform for Multi-stain IHC and Immunology?
Amaya Gallagher-Syed, Elena Pontarini, Myles J. Lewis +2
This study evaluates the generalisation capabilities of state-of-the-art histopathology foundation models on out-of-distribution multi-stain autoimmune Immunohistochemistry dataset…
MUSTANG: Multi-Stain Self-Attention Graph Multiple Instance Learning Pipeline for Histopathology Whole Slide Images
Amaya Gallagher-Syed, Luca Rossi, Felice Rivellese +4
Whole Slide Images (WSIs) present a challenging computer vision task due to their gigapixel size and presence of numerous artefacts. Yet they are a valuable resource for patient di…
Automated segmentation of rheumatoid arthritis immunohistochemistry stained synovial tissue
Amaya Gallagher-Syed, Abbas Khan, Felice Rivellese +4
Rheumatoid Arthritis (RA) is a chronic, autoimmune disease which primarily affects the joint's synovial tissue. It is a highly heterogeneous disease, with wide cellular and molecul…