1 citations · 2 across the 3 of their papers we have counts for
4 papers
Integrated Population Balance and Multiphysics Modeling for Predicting Undesired Agglomeration in Small Molecule Manufacturing
Prakitr Srisuma, Peter Hou, Shashank Venkat Muddu +3
Agitated filter dryers (AFDs) are a crucial unit operation in small molecule manufacturing that enables simultaneous filtration, washing, and drying of active pharmaceutical ingred…
Line Tension Reshapes Nucleation at Surface Edges: A Generalized Theory for Nanopore Activation
Yanchen Wu, Martin Z. Bazant, Allan S. Myerson +1
Heterogeneous nucleation at surface edges is pervasive across nature and industry, yet the role of line tension, arising from asymmetric capillary interactions at geometric singula…
Mechanistic Modeling of Lipid Nanoparticle (LNP) Precipitation via Population Balance Equations (PBEs)
Sunkyu Shin, Cedric Devos, Aniket Pradip Udepurkar +3
Lipid nanoparticles (LNPs) are precisely engineered drug delivery carriers commonly produced through controlled mixing processes, such as nanoprecipitation. Since their delivery ef…
Emergent kinetics of in vitro transcription from interactions of T7 RNA polymerase and DNA
Nathan M. Stover, Marieke De Bock, Julie Chen +4
The in vitro transcription reaction (IVT) is of growing importance for the manufacture of RNA vaccines and therapeutics. While the kinetics of the microscopic steps of this reactio…