5 papers
Authentic Multinational Federated Time-to-Event Analyses Among People with HIV in Latin America
Kaixing Liu, Zhuohui J. Liang, Fabio Paredes +12
Multinational HIV cohort studies face regulatory barriers to cross-border sharing of individual participant data, limiting centralized pooled analyses. Federated statistical method…
PDA in Action: Ten Principles for High-Quality Multi-Site Clinical Evidence Generation
Yong Chen, Jiayi Tong, Yiwen Lu +13
Background: Distributed Research Networks (DRNs) offer significant opportunities for collaborative multi-site research and have significantly advanced healthcare research based on…
Empowering Clinical Trial Design through AI: A Randomized Evaluation of PowerGPT
Yiwen Lu, Lu Li, Dazheng Zhang +20
Sample size calculations for power analysis are critical for clinical research and trial design, yet their complexity and reliance on statistical expertise create barriers for many…
Enabling Inclusive Systematic Reviews: Incorporating Preprint Articles with Large Language Model-Driven Evaluations
Rui Yang, Jiayi Tong, Haoyuan Wang +8
Background. Systematic reviews in comparative effectiveness research require timely evidence synthesis. Preprints accelerate knowledge dissemination but vary in quality, posing cha…
OrigamiPlot: An R Package and Shiny Web App Enhanced Visualizations for Multivariate Data
Yiwen Lu, Jiayi Tong, Yuqing Lei +8
We introduce OrigamiPlot, an open-source R package and Shiny web application designed to enhance the visualization of multivariate data. This package implements the origami plot, a…