117 citations · 131 across the 5 of their papers we have counts for
7 papers
An Uncertainty-Guided Digital Twin Framework for Online Adaptive Proton Therapy in Head and Neck Cancer: A Feasibility Study
Yizhou Wu, Ryan J. Sanford, Huiqiao Xie +12
Objective: Head and neck (HN) proton therapy spans six to seven weeks of anatomical change, while offline replanning takes about a week. We present an uncertainty-guided digital tw…
A digital-twin framework for forecasting treatment-day imaging with contour uncertainty in adaptive proton radiotherapy
Yizhou Wu, Jie Ding, Justin Roper +6
Head-and-neck anatomy changes over a six-to-seven-week proton course, and the anatomy of a later week cannot be imaged when the plan is made. We present a digital-twin framework th…
Clinically Interpretable Survival Risk Stratification in Head and Neck Cancer Using Bayesian Networks and Markov Blankets
Keyur D. Shah, Ibrahim Chamseddine, Xiaohan Yuan +8
Purpose: To identify a clinically interpretable subset of survival-relevant features in HN cancer using Bayesian Network (BN) and evaluate its prognostic and causal utility. Method…
Streamlined Pin-Ridge-Filter Design for Single-energy Proton FLASH Planning
Chaoqiong Ma, Jun Zhou, Chih-Wei Chang +5
Purpose: This study explored the feasibility of a streamlined pin-shaped ridge filter (pin-RF) design for single-energy proton FLASH planning. Methods: An inverse planning framewor…
Synthetic CT Generation from MRI using 3D Transformer-based Denoising Diffusion Model
Shaoyan Pan, Elham Abouei, Jacob Wynne +10
Magnetic resonance imaging (MRI)-based synthetic computed tomography (sCT) simplifies radiation therapy treatment planning by eliminating the need for CT simulation and error-prone…
CBCT-Based Synthetic CT Image Generation Using Conditional Denoising Diffusion Probabilistic Model
Junbo Peng, Richard L. J. Qiu, Jacob F Wynne +8
Background: Daily or weekly cone-beam computed tomography (CBCT) scans are commonly used for accurate patient positioning during the image-guided radiotherapy (IGRT) process, makin…
A Retrospective Study on the Investigation of Potential Clinical Benefits of Online Adaptive Proton Therapy for Head and Neck Cancer
Chih-Wei Chang, Duncan Bohannon, Zhen Tian +6
Online adaptive proton therapy (APT) is an ideal solution theoretically, which however is challenging to proton clinics. Although multiple groups have been endeavoring to develop o…