2 papers
physics.bio-ph2025
Molecular Determinants of Orthosteric-allosteric Dual Inhibition of PfHT1 by Computational Assessment
Decheng Kong, Jinlong Ren, Zhuang Li +5
To overcome antimalarial drug resistance, carbohydrate derivatives as selective PfHT1 inhibitor have been suggested in recent experimental work with orthosteric and allosteric dual…
q-bio.QM2020
Accelerating drug repurposing for COVID-19 via modeling drug mechanism of action with large scale gene-expression profiles
Lu Han, G. C. Shan, B. F. Chu +4
The novel coronavirus disease, named COVID-19, emerged in China in December 2019, and has rapidly spread around the world. It is clearly urgent to fight COVID-19 at global scale. T…