4 papers
A Comparative Study of Large Language Models and Human Personality Traits
Wang Jiaqi, Wang bo, Guo fa +2
Large Language Models (LLMs) have demonstrated human-like capabilities in language comprehension and generation, becoming active participants in social and cognitive domains. This…
A DNA-Centric Mechanism for Protein Targeting in 6mA Methylation
Li Yang, Dongbo Wang
How DNA-binding proteins locate specific genomic targets remains a central challenge in molecular biology. Traditional protein-centric approaches, which rely on wet-lab experiments…
Language-Inspired Modeling Reveals Redundant Encoding of N4-acetylcytidine(ac4C) Modifications in mRNA
Li Yang, Dongbo Wang
The ac4C modification on mRNA has been demonstrated to be associated with various diseases; however, its molecular mechanism remains unclear. The wet lab experiments produced relat…
Interpretable structural-semantic decoding reveals language-like organisation of regulatory information in DNA
Li Yang, Dongbo Wang
Decoding how linear DNA encodes regulatory information remains a central challenge. Existing decoding approaches lack interpretability and struggle to reveal the underlying coding…