2 papers
stat.ME2025
Bayesian adaptive randomization in the I-SPY2 sequential multiple assignment randomized trial
Peter Norwood, Christina Yau, Denise Wolf +4
The I-SPY2 phase 2 clinical trial is a long-running platform trial that evaluates neoadjuvant treatments for locally advanced breast cancer, assigning subjects to novel agents usin…
stat.ME2024
Adaptive Randomization Methods for Sequential Multiple Assignment Randomized Trials (SMARTs) via Thompson Sampling
Peter Norwood, Marie Davidian, Eric Laber
Response-adaptive randomization (RAR) has been studied extensively in conventional, single-stage clinical trials, where it has been shown to yield ethical and statistical benefits,…