2 papers
cs.CE2026
Multi-Objective Amortized CDRH3 Sequence Sampling Diversifies Promising Antibody Candidates
Joseph D. Viviano, Almer van der Sloot, Quentin Fournier +3
Antibody therapeutics have transformed treatment across diverse therapeutic areas and have become central to modern medicine. While recent machine learning approaches aim to accele…
cs.LG2025
Structure-Aligned Protein Language Model
Can Chen, David Heurtel-Depeiges, Robert M. Vernon +3
Protein language models (pLMs) pre-trained on vast protein sequence databases excel at various downstream tasks but often lack the structural knowledge essential for some biologica…