1 citations · 1 across the 2 of their papers we have counts for
3 papers
Predicting Mutational Signature Exposures from H&E Whole Slide Images: A Pan-Cancer Feasibility Study
Flavio Sartori, Cesare Rollo, Isabella Caranzano +3
Mutational signatures reveal cancer-driving processes with clinical relevance: MMR-deficient tumors respond better to immunotherapy, HRD tumors are sensitive to PARP inhibitors, an…
Sparsity is All You Need: Rethinking Biological Pathway-Informed Approaches in Deep Learning
Isabella Caranzano, Corrado Pancotti, Cesare Rollo +4
Biologically-informed neural networks typically leverage pathway annotations to enhance performance in biomedical applications. We hypothesized that the benefits of pathway integra…
JanusDDG: A Thermodynamics-Compliant Model for Sequence-Based Protein Stability via Two-Fronts Multi-Head Attention
Guido Barducci, Ivan Rossi, Francesco Codicè +6
Understanding how residue variations affect protein stability is crucial for designing functional proteins and deciphering the molecular mechanisms underlying disease-related mutat…