98 citations · 335 across the 42 of their papers we have counts for
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Exact Analysis of Intrinsic Qualitative Features of Phosphorelays using Mathematical Models
Michael Knudsen, Elisenda Feliu, Carsten Wiuf
Phosphorelays are a class of signaling mechanisms used by cells to respond to changes in their environment. Phosphorelays (of which two-component systems constitute a special case)…
Variable elimination in chemical reaction networks with mass action kinetics
Elisenda Feliu, Carsten Wiuf
We consider chemical reaction networks taken with mass action kinetics. The steady states of such a system are solutions to a system of polynomial equations. Even for small systems…
Preclusion of switch behavior in reaction networks with mass-action kinetics
Elisenda Feliu, Carsten Wiuf
We provide a Jacobian criterion that applies to arbitrary chemical reaction networks taken with mass-action kinetics to preclude the existence of multiple positive steady states wi…
Variable elimination in post-translational modification reaction networks with mass-action kinetics
Elisenda Feliu, Carsten Wiuf
We define a subclass of Chemical Reaction Networks called Post-Translational Modification systems. Important biological examples of such systems include MAPK cascades and two-compo…
Enzyme sharing as a cause of multistationarity in signaling systems
Elisenda Feliu, Carsten Wiuf
Multistationarity in biological systems is a mechanism of cellular decision making. In particular, signaling pathways regulated by protein phosphorylation display features that fac…