activity
20062026
most citedIdentifying parameter regions for multistationarity

98 citations · 335 across the 42 of their papers we have counts for

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19 papers · 1 filter

q-bio.MN2024

The generic geometry of steady state varieties

Elisenda Feliu, Oskar Henriksson, Beatriz Pascual-Escudero

We answer several fundamental geometric questions about reaction networks with power-law kinetics, on topics such as generic finiteness of the number of steady states, robustness,…

q-bio.MN2024

Positive equilibria in mass action networks: geometry and bounds

Murad Banaji, Elisenda Feliu

Any mass action network gives rise to a parameterised family of polynomial equations whose positive solutions are the positive equilibria of the network. Here, we consider alternat…

q-bio.MN2022★ 9 cited

Topological descriptors of the parameter region of multistationarity: deciding upon connectivity

Máté L. Telek, Elisenda Feliu

Switch-like responses arising from bistability have been linked to cell signaling processes and memory. Revealing the shape and properties of the set of parameters that lead to bis…

q-bio.MN2022★ 2 cited

Parameter region for multistationarity in site phosphorylation networks

Elisenda Feliu, Nidhi Kaihnsa, Timo de Wolff +1

Multisite phosphorylation is a signaling mechanism well known to give rise to multiple steady states, a property termed multistationarity. When phosphorylation occurs in a sequenti…

q-bio.MN2020★ 4 cited

The kinetic space of multistationarity in dual phosphorylation

E. Feliu, N. Kaihnsa, T. de Wolff +1

Multistationarity in molecular systems underlies switch-like responses in cellular decision making. Determining whether and when a system displays multistationarity is in general a…

q-bio.MN2019

Symbolic proof of bistability in reaction networks

Angélica Torres, Elisenda Feliu

Deciding whether and where a system of parametrized ordinary differential equations displays bistability, that is, has at least two asymptotically stable steady states for some cho…