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physics.bio-ph2025
Exploration of the potential energy surface for the conformational interconversion of the amyloid peptide at the fibril end
Yasuhiro Oishi, Motoharu Kitatani, Kichitaro Nakajima +2
The formation of amyloid fibrils comprising amyloid (A) peptides is associated with the pathology of Alzheimer's disease. In this study, we theoretically investigated the A$…
physics.bio-ph2021★ 2 cited
Acceleration of amyloid fibril formation by multichannel sonochemical reactor
Kentaro Noi, Kichitaro Nakajima, Keiichi Yamaguchi +5
Formation of amyloid fibrils of various amyloidogenic proteins is dramatically enhanced by ultrasound irradiation. For applying this phenomenon to the study of protein aggregation…