2 papers
physics.bio-ph2026
Nuclear mechanics controls the temporal dynamics of cell unjamming
Leon Hillmann, Quirine J. S. Braat, Pablo Gottheil +9
Cell unjamming in dense tissues is a complex but essential process in embryogenesis and cancer metastasis. Increasing evidence suggests that nuclear mechanics and density effects p…
physics.bio-ph2024
Self organisation of invasive breast cancer driven by the interplay of active and passive nematic dynamics
Pablo Gottheil, Saraswat Bhattacharyya, Kolya Lettl +12
In invasive breast cancer, cell clusters of varying sizes and shapes are embedded in the fibrous extracellular matrix (ECM). Although the prevailing view attributes this structure…