3 papers
physics.bio-ph2026
Nuclear mechanics controls the temporal dynamics of cell unjamming
Leon Hillmann, Quirine J. S. Braat, Pablo Gottheil +9
Cell unjamming in dense tissues is a complex but essential process in embryogenesis and cancer metastasis. Increasing evidence suggests that nuclear mechanics and density effects p…
physics.bio-ph2024
Formation of motile cell clusters in heterogeneous model tumors: the role of cell-cell alignment
Quirine J. S. Braat, Cornelis Storm, Liesbeth M. C. Janssen
Circulating tumor cell clusters play an important role in the metastatic cascade. These clusters can acquire a migratory and more invasive phenotype, and coordinate their motion to…
physics.bio-ph2024
Shape matters: Inferring the motility of confluent cells from static images
Quirine J. S. Braat, Giulia Janzen, Bas C. Jansen +3
Cell motility in dense cell collectives is pivotal in various diseases like cancer metastasis and asthma. A central aspect in these phenomena is the heterogeneity in cell motility,…