5 citations · 12 across the 5 of their papers we have counts for
5 papers
Constraint-based modeling and simulation of cell populations
M. Di Filippo, C. Damiani, R. Colombo +2
The intratumor heterogeneity has been recognized to characterize cancer cells impairing the efficacy of cancer treatments. We here propose an extension of constraint-based modeling…
An ensemble approach to the study of the emergence of metabolic and proliferative disorders via Flux Balance Analysis
Chiara Damiani, Riccardo Colombo, Sara Molinari +5
An extensive rewiring of cell metabolism supports enhanced proliferation in cancer cells. We propose a systems level approach to describe this phenomenon based on Flux Balance Anal…
GPU-powered Simulation Methodologies for Biological Systems
Daniela Besozzi, Giulio Caravagna, Paolo Cazzaniga +3
The study of biological systems witnessed a pervasive cross-fertilization between experimental investigation and computational methods. This gave rise to the development of new met…
An Analysis on the Influence of Network Topologies on Local and Global Dynamics of Metapopulation Systems
Daniela Besozzi, Paolo Cazzaniga, Dario Pescini +1
Metapopulations are models of ecological systems, describing the interactions and the behavior of populations that live in fragmented habitats. In this paper, we present a model of…
A study on the combined interplay between stochastic fluctuations and the number of flagella in bacterial chemotaxis
Daniela Besozzi, Paolo Cazzaniga, Matteo Dugo +2
The chemotactic pathway allows bacteria to respond and adapt to environmental changes, by tuning the tumbling and running motions that are due to clockwise and counterclockwise rot…