64 citations · 95 across the 8 of their papers we have counts for
9 papers
Control in Boolean networks with model checking
Laura Cifuentes-Fontanals, Elisa Tonello, Heike Siebert
Understanding control mechanisms in biological systems plays a crucial role in important applications, for instance in cell reprogramming. Boolean modeling allows the identificatio…
Classifier construction in Boolean networks using algebraic methods
Robert Schwieger, Matías R. Bender, Heike Siebert +1
We investigate how classifiers for Boolean networks (BNs) can be constructed and modified under constraints. A typical constraint is to observe only states in attractors or even mo…
Control Strategy Identification via Trap Spaces in Boolean Networks
Laura Cifuentes Fontanals, Elisa Tonello, Heike Siebert
The control of biological systems presents interesting applications such as cell reprogramming or drug target identification. A common type of control strategy consists in a set of…
Boolean analysis of lateral inhibition
Elisa Tonello, Heike Siebert
We study Boolean networks which are simple spatial models of the highly conserved Delta-Notch system. The models assume the inhibition of Delta in each cell by Notch in the same ce…
Representing Model Ensembles as Boolean Functions
Robert Schwieger, Heike Siebert
Families of ODE models characterized by a common sign structure of their Jacobi matrix are investigated within the formalism of qualitative differential equations. In the context o…
Basins of Attraction, Commitment Sets and Phenotypes of Boolean Networks
Hannes Klarner, Frederike Heinitz, Sarah Nee +1
The attractors of Boolean networks and their basins have been shown to be highly relevant for model validation and predictive modelling, e.g., in systems biology. Yet there are cur…